Exosomes are small, spherical to cup-shaped membrane vesicles (30-100 nm in diameter) that are generated in the late endosomal compartment through inward budding of multivesicular bodies (MVBs). They are comprised of lipids, proteins, and mRNA which can be transferred to surrounding cells in order to nourish or communicate with them. They are derived from mesenchymal stem cells (MSC’s) which have been shown to be well tolerated by the immune system which makes for effective and safe drug delivery. In experimental and clinical settings, exosomes have been isolated from a range of cell lines as well as from biological fluids (serum and plasma) and other body fluids. Structurally, exosomes contain multiple proteins, lipids, DNA, RNAs (mRNA, miRNA, ncRNA), and even biomolecules of viruses/prions.
ERP™ (Exosome Rich Plasma) sources from umbilical cord blood is a great source for research as well as future clinical applications. MonoTx is committed to providing the highest quality products to the community.